In view of the challenges of the current coronavirus (SARS-CoV-2) pandemic, the International Society of Ultrasound in Obstetrics and Gynecology (ISUOG) has compiled the following expert-opinion-based guidance on safe use of personal protective equipment (PPE) and how to reduce the hazard of SARS-CoV-2 infection for clinicians undertaking ultrasound examinations (physicians, sonographers and allied professionals).