Cervical cancer, a malignancy that arises from the cervix, is the fourth most common cancer in women, accounting for an estimated 604,000 new cases and 342,000 deaths worldwide. The most frequent histotypes are HPV-related squamous cell carcinoma and adenocarcinoma.
Cancer of the uterine cervix has traditionally been staged clinically, but surgical and radiologic evaluations are now part of the staging assessment. Ultrasound is an effective tool for cervical cancer work-up and, in experienced hands, can be an effective alternative to MRI in diagnosing cervical cancer and detecting the extent of loco-regional disease in the pelvis.
Whilst MRI has been shown to have the best sensitivity and specificity in assessing the size of the lesion, ultrasound provides comparable information for staging when performed by experienced operators. Patients with cervical cancer should be staged according to 2021 TNM classification.
This VISUOG chapter serves as an invaluable resource for delving into the proper definition, the epidemiology, pathogenesis, and histopathology of cervical cancer. Additionally, it outlines the pivotal role of ultrasound in cervical cancer staging, specifying the ultrasound parameters that influence management and should be included in a systematic checklist. These may include tumor identification, tumor size, depth of stromal invasion, bladder and rectal invasion, and more, all outlined comprehensively in the chapter.
To learn more about the prognosis, prevention, and management of cervical cancer, and to see visuals of ultrasound staging, read the VISUOG chapter on cervical cancer for free throughout June.
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